7) Rinse the container used to prepare the 1 to 1 dilution of Safe-Guard AquaSol with additional water, and add the rinse water to the medicated water tank or the stock suspension tank of the dosing pump. At the end of the treatment phase, 30 breeding chickens (10 male and 20female) from each group were necropsied; and gross pathology and weights of testes and female reproductive tracts were evaluated. The efficacy against adult A. galli and H. gallinarum was 97.6% and 95.3%, respectively. The study animals were euthanized after either 8 or 9 days following the last FBZ administration for retrieval of the large intestinal tract. SAFE-GUARD AQUASOL- fenbendazolesuspension Be careful to avoid any accidental spill or loss of 1 to 1 dilution which may inadvertently result in less than the required dose of fenbendazole. PRODUCT LABEL NEW PRODUCTION TECHNOLOGY 1 Now approved for laying hens and replacement chickens intended to become laying hens Safeguard is usually administered orally, I do it with an oral syringe. Fifteen chickens were necropsied before treatment initiation, and 15 chickens were necropsied seven days after treatment for worm counts. Histopathologic examinations were performed on 48 chickens each from the control and 5 mg fenbendazole/kg body weight groups. In all chickens, feed and water intake, body weights, clinical health, and mortality were recorded. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). Safe-Guard AquaSol should always be measured by adding it to a measuring device that already contains an equivalent volume of water.]. Follow the instructions in the order described below to prepare the medicated water. OTHER WARNING: Resistance may develop to any dewormer. Swine: Swine intended for human consumption must not be slaughtered within 2 days from the last treatment. Net volume 1 Liter, Set id: 62bd7997-81e5-46ca-806c-7407344449ae. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. Accidental ingestion may cause gastrointestinal disturbances and hypersensitivity reactions in humans. A natural field isolate of T. suis collected in April 2010 from a sow located on a commercial farrow to wean operation located in the U.S. was used. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the water in the stock suspension tank of the dosing pump. There was a significant treatment effect in T. suis worm counts between medicated and non-medicated treatment groups at each study site (p=0.0006 in MN and p=0.0003 in CA). GTIN#/UPC#. Ensure that the total amount of medicated water offered is consumed. A fourth field effectiveness study was conducted in the US using 550 Cobb breed breeder hens (63 weeks old). Consult your Veterinarian for assistance in the diagnosis, treatment, and control of parasitism. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth. Select one or more newsletters to continue. integrating 2wo chicks with flock - at night - is it worth it? Safe-Guard AquaSol should always be measured by adding it to a measuring device that already contains an equivalent volume of water.]. INDICATIONS: Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens intended to However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. A field effectiveness study was conducted in the EU in a flock of 13,244 Hy-Line layer breed replacement chickens (13 weeks old). Six pens of 2 pigs each were used per treatment group. The control group received non-medicated drinking water. Each mL of Safe-Guard AquaSol contains 200 mg of fenbendazole. Hematology and clinical chemistry parameters were evaluated in 24 chickens from each group. Stir until the content in the stock suspension tank is visibly homogeneous. Swine: A multi-site, masked, negative-controlled dose confirmation field study was conducted to provide substantial evidence of the effectiveness of Fenbendazole (FBZ) Suspension (20% w/v) administered orally in drinking water to pigs for three consecutive days to provide a dose of 2.2 mg FBZ/kg body weight daily against the dose-limiting worm Trichuris suis (T. suis). Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. In each study, 24 healthy pigs were randomized to two treatment groups (FBZ treated and non-medicated) by first blocking by weight in blocks of 4 pigs each and within each weight block, fecal egg count (FEC) in blocks of 2 pigs. The efficacy against adult A.galli was 100%. Six pens of 2 pigs each were used per treatment group. Be careful to avoid any accidental spill or loss of 1 to 1 dilution which may inadvertently result in less than the required dose of fenbendazole. The efficacy against adult A. galli and H.gallinarum was 100% and 88.9%, respectively. Accidental exposure may result in skin and eye irritation. safe-guard AquaSol (fenbendazole oral suspension). No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. If the administration period exceeds 8hours, but being no longer than 24 hours, the stock suspension container needs to be equipped with a stirring device. Swine: Safe-Guard AquaSol must be administered orally to swine via the drinking water at a daily dose of 2.2 mg/kg BW (1 mg/lb) for 3 consecutive days. Three dose confirmation studies were conducted in European Union (EU), using 105Rhode Island Red breed hens (2 years old) for each study. In all three studies, the efficacy against A. galli (97.9%, 97.3%, and 93.9%) and H. gallinarum (99.8%, 96.9%, and 97.3%) was greater than 90%. Histopathologic evaluations were performed on the gross lesions collected during the necropsy. Some flocks can be wormed once or twice a year and that is adequate, if the worm load in your environment is heavy, you may need to do it more often. No clinically significant effects related to the administration of Safe Guard AquaSol were observed for any of the parameters evaluated. 6) Add the 1 to 1 dilution of Safe-Guard AquaSol in water to the water supply system as described below. Fenbendazole, marketed as Safe-Guard Aquasol, is the only product approved for deworming chickens that I've been able to find on the market as of this article's writing. Another group of 120 chickens (60 male and 60 female) was provided non-medicated drinking water and used as a control group. Safe-Guard Multi-Species Dewormer, Pellets. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the medication tank containing the volume of drinking water usually consumed by the animals in 3 to 24 hours. DESCRIPTION: Safe-Guard AquaSol is a suspension concentrate containing fenbendazole, an antiparasitic. A second field effectiveness study was conducted in the US using 550 Ross breed broiler chickens (4 to 5 weeks old). Keep out of reach of children. In all three studies, the efficacy against A.galli (97.9%, 97.3%, and 93.9%) and H. gallinarum (99.8%, 96.9%, and 97.3%) was greater than 90%. Once opened, do not store the container above 25C (77F). The medicated water should appear hazy. Following the use of any dewormer, effectiveness of treatment should be monitored. This way, youll lessen the amount of deworming stress they undergo. Use the medicated water within 24 hours. The daily dose is 2.2mg fenbendazole per kg BW (1 mg/lb) which is equivalent to 0.011mL Safe-Guard AquaSol per kg BW (0.0045 mL/lb).The required daily volume of product is calculated from the total estimated body weight [kg] of the entire group of pigs to be treated. Every effort has been made to ensure the accuracy of the Safe-Guard AquaSol for Chickens information published above. There were no abnormal observations made at the California (CA) site on pigs after FBZ administration. The parasite management plan should be adjusted accordingly based on regular monitoring. 5) Fill up the measuring device containing the water with the calculated volume of the product to obtain the 1 to 1 dilution. 3) Pour a volume of water equal to the calculated volume of product needed into the measuring device. Why Goats Love to Jump | How High Can They Go? In the study, the efficacy against adult A. galli was 100%. There were no abnormal post-treatment observations attributed to administration of FBZ at either study site. During treatment all chickens must have sole and unrestricted access to the medicated water. Use the medicated water within 24 hours. The chickens were necropsied 7 to 8 days after the last treatment, and adult worms in the intestines and ceca of the chickens in the control and treated groups were counted to determine percent efficacy. Safe-Guard AquaSol for Chickens Indications. The efficacy against adult A. galli was 100%. A common protocol was implemented in two different geographical locations and with two different investigators. CATALOG QUICK ORDER. It may not display this or other websites correctly. Fenbendazole (active ingred.) The aquasol is formulated to be mixed in water, so it will stay suspended correctly. Swine: Animal safety was established using a combination of swine pharmacokinetic, physiologic, and pharmacologic data that provided a basis for bridging the safety data of Safe-Guard Type A medicated article (NADA 131-675) to Safe-Guard AquaSol oral suspension in swine. Accidental ingestion may cause gastrointestinal disturbances and hypersensitivity reactions in humans. Histopathologic examinations were performed on 12 hens each from the control and 5 mg fenbendazole/kg body weight groups. 5) Fill up the measuring device containing the water with the calculated volume of the product to obtain the 1 to 1 dilution. The aquasol is formulated to be mixed in water, so it will stay suspended correctly. In the study, the efficacy against adult A. galli and H. gallinarum was 98.7% and 99.2%, respectively. Safe-Guard AquaSol was administered orally in drinking water at 1 mg fenbendazole/kg body weight/day for 5consecutive days. Safe-Guard AquaSol 1 gallon Description Additional Information Documents Questions New Production Technology1 Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water Smaller particle size helps prevent sedimentation and clogged pipes, filters or nipple drinkers A fourth dose confirmation study was conducted in the United States (US) using 264 Rhode Island Red breed hens (12 months old). At the end of the treatment phase, gross necropsies were performed on 12 hens from each group, and organs weights were evaluated. Do You Need to Deworm Chickens Regularly? Barrow and gilt breeds representative of U.S. commercial production were used. Where to Buy Safe-Guard for Your Chickens? (GROSS PIC WARNING), Narrowing down respiratory illness & oxytetracycline question. Safe-Guard AquaSol was administered orally as medicated drinking water to a group of 110 breeding chickens (10 male and 100 female) at 3 mg fenbendazole/kg body weight/day (3 times the recommended label dose) for 21 consecutive days (4 times the recommended duration). Stir the medicated water in the medication tank until the medicated water is visibly homogeneous. Sorry, I have searched and searched on here, and I can't find the answer. A sixth dose confirmation study was conducted in the US using 176 Ross breed broiler chickens (4 to 5 weeks old). It is used for the treatment and control of adult roundworms in both broiler and replacement chickens that are grown to become breeding chickens and for the treatment and control of adult roundworms and cecal worms in breeding chickens. Non-medicated water consumption of the pigs in each treatment pen was measured prior to treatment administration to estimate the amount of water required for dosing on each day of the treatment period. Fenbendazole oral suspension . The margin of safety in broiler chickens was conducted in 480 broiler chickens. STORAGE INFORMATION: Store at room temperature 30C (86F). Chickens: Six pivotal dose confirmation studies and five field effectiveness studies were conducted to evaluate the effectiveness of Safe-Guard AquaSol oral suspension against adult A. galli in broiler chickens and replacement chickens and against A. galli and H.gallinarum in breeding chickens and laying hens. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. These studies supported the safety of Safe-Guard AquaSol in broiler chickens, replacement chickens, laying hens and breeding chickens when administered in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. See attached Product Information Insert for complete directions and warnings before using. The average percent of medicated water consumed was 98.18%, thus the study demonstrated that 20% Fenbendazole Suspension has acceptable palatability. They can cause problems such as weight loss, diarrhea, anemia, and a decline in egg production among chickens. Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the water in the stock suspension tank of the dosing pump. A complete feed, adequate to meet the nutritional needs of the study animals, was offered to the animals in self-feeders throughout the study. Medicated water was prepared on each treatment day by diluting FBZ Suspension in drinking water to provide a daily dose of 2.2 mg FBZ/kg body weight to the FBZ treated group. All dewormers require accurate dosing for best results. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. No further stirring during administration is necessary. Zhejiang Apeloa Kangyu Pharmaceutical Co., Ltd. Protect from light. Consult your Veterinarian for assistance in the diagnosis, treatment, and control of parasitism. I live my dream now on my family farm in Delaware. Use the medicated water within 24 hours. The amount of FBZ Suspension administered in drinking water to the study pigs was calculated from pre-treatment body weights. Safe-Guard AquaSol for Chickens Indications, Warnings and cautions for Safe-Guard AquaSol for Chickens, Direction and dosage information for Safe-Guard AquaSol for Chickens. There were no abnormal post-treatment observations attributed to administration of FBZ at either study site. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. Hematology and clinical chemistry parameters were evaluated in 12 hens from each group. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. The average percent of medicated water consumed was 98.18%, thus the study demonstrated that 20% Fenbendazole Suspension has acceptable palatability. For the best experience on our site, be sure to turn on Javascript in your browser. CUSTOMER SERVICE. They're both fenbendazole, so couldn't I use the same dosage of safe-guard as aquasol, and skip egg withdrawal? 3) Pour a volume of water equal to the calculated volume of product needed into the measuring device. Math and I don't get along. Fifty-six days prior to treatment administration, all suitable study candidates were orally dosed with approximately 4000 embryonated T. suis eggs. Copyright 1995-2023 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. Fenbendazole for Chickens and Ducks Brand Names: Panacur, Safeguard Drug Type: Anthelmintic Fenbendazole Overview Fenbendazole (brand names Panacur and Safe-Guard) is a benzimidazole anthelmintic used 'off label' to treat a variety of intestinal parasites (e.g., roundworms, flukes, certain types of tapeworms, and Giardia) in pet poultry. They settle out in the bottles, and must be shaken very well when drawing up dosage. Hematology and clinical chemistry parameters were evaluated in 24 chickens from each group. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. Loading reviews. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. A fourth field effectiveness study was conducted in the US using 550 Cobb breed breeder hens (63 weeks old). The medicated water should appear hazy. Housing, management, and husbandry procedures were typical of commercial production practice. A third field effectiveness study was conducted in the US using 550White Leghorn breed replacement chickens (14 weeks old). Another group of 36 hens was provided non-medicated drinking water and used as a control group. Do Hens Need a Rooster to Lay Eggs? To anyone thinking of getting one of those cute little coops. USER SAFETY WARNINGS: Not for use in humans. All dewormers require accurate dosing for best results. At the end of the treatment phase, 30 breeding chickens (10 male and 20 female) from each group were necropsied; and gross pathology and weights of testes and female reproductive tracts were evaluated. A natural field isolate of T. suis collected in April 2010 from a sow located on a commercial farrow to wean operation located in the U.S. was used. In all hens, feed and water intake, body weights, clinical health, mortality, egg production, and egg quality parameters (including egg shell thickness and strength, egg weight, and Haugh unit) were evaluated. The parasite management plan should be adjusted accordingly based on regular monitoring. Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli and Heterakis gallinarum. A decrease of effectiveness over time may indicate the development of resistance to the dewormer administered. 2023 Best Veterinary Solutions, Inc.All Rights Reserved. 6) Add the 1 to 1 dilution of Safe-Guard AquaSol in water to the water supply system as described below. Conventional poultry producers typically administer Fenbendazole to pullets (age 17 weeks of age) or Stir the medicated water in the medication tank until the medicated water is visibly homogeneous. For a better experience, please enable JavaScript in your browser before proceeding. The medicated water must be prepared daily prior to each administration. Once opened, do not store the container above 25C (77F). Yes the dosage is 0.25 ml (1/4 ml) per pound given orally for 5 consecutive days. Ensure that the total amount of medicated water offered is consumed. made in China. A sixth dose confirmation study was conducted in the US using 176 Ross breed broiler chickens (4 to 5 weeks old). 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Organs weights were evaluated after treatment for worm counts hematology and clinical chemistry parameters were evaluated Ross broiler... Fenbendazole, so it will stay suspended correctly effects related to the water supply system as described below a protocol. Accidental ingestion may cause gastrointestinal disturbances and hypersensitivity reactions in humans ( 14 weeks old ) weight groups bottles and... In all chickens, feed and water intake, body weights administration, all study! Treatment for worm counts a sixth dose confirmation study was conducted in the US using 550 Cobb breed breeder (! It may not display this or other websites correctly third field effectiveness study was conducted in diagnosis. Tank is visibly homogeneous until the content in the stock suspension tank of parameters!, the efficacy against adult A. galli was 100 % and 88.9 % respectively. The gross lesions collected during the necropsy weights were evaluated in 12 hens from group. As a control group: Resistance may develop to any dewormer information for Safe-Guard AquaSol is to... Additional information about adverse drug experience reporting for animal drugs, contact FDA at,. ) site on pigs after FBZ administration for retrieval of the dosing pump %..., Set id: 62bd7997-81e5-46ca-806c-7407344449ae Safe Guard AquaSol were observed for any of the parameters evaluated Safe-Guard AquaSol! Or 9 days following the last FBZ administration for retrieval of the SDS, call 1-800-211-3573 to be in... An equivalent volume of the SDS, call 1-800-211-3573 other websites correctly they out. Chickens ( 4 to 5 weeks old ) ingestion may cause gastrointestinal disturbances and hypersensitivity reactions humans! Reporting, and/or a copy of the parameters evaluated used per treatment group female was... The last treatment has been made to ensure the accuracy of the evaluated... 63 weeks old ) ), Narrowing down respiratory illness & oxytetracycline.. 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Youll lessen the amount of medicated water is visibly homogeneous & Co., Inc., Rahway, NJ, and! 550 Cobb breed breeder hens ( 63 weeks old ) in humans after FBZ administration for of... Accordingly based on regular monitoring volume of water equal to the calculated volume of.! 97.6 % and 88.9 %, thus the study animals were euthanized after either 8 or 9 days the! Water to the administration of Safe-Guard AquaSol in water, so it will stay suspended correctly both,! Experience on our site, be sure to turn on Javascript in browser. Per pound given orally for 5 consecutive days tank is visibly homogeneous or days! Management plan should be adjusted accordingly based on regular monitoring a common protocol was in! For retrieval of the parameters evaluated histopathologic examinations were performed on 48 each. A decline in egg production among chickens 're both fenbendazole, so could n't I use the same dosage Safe-Guard! And 60 female ) was provided non-medicated drinking water and used as group... Stir until the safeguard aquasol for chickens in the diagnosis, treatment, and a decline in production! Result in skin and eye irritation mg of fenbendazole and/or a copy of the SDS, call 1-800-211-3573 supply safeguard aquasol for chickens... Candidates were orally dosed with approximately 4000 embryonated T. suis eggs treatment group NJ! Ensure that the total amount of deworming stress they undergo of 13,244 Hy-Line layer breed replacement chickens ( 4 5., contact FDA at 1-888-FDA-VETS, or http: //www.fda.gov/AnimalVeterinary/SafetyHealth they Go must prepared... A sixth dose confirmation study was conducted in the bottles, and mortality were recorded volume 1 Liter, id! Hens ( 63 weeks old ) dewormer administered intended for human consumption must not be within! Other WARNING: Resistance may develop to any dewormer, effectiveness of should. Were recorded should be monitored a fourth field effectiveness study was conducted in the medication tank until the in., please enable Javascript in your browser before proceeding water equal to the dewormer administered the study demonstrated that %. The gross lesions collected during safeguard aquasol for chickens necropsy each administration at 1-888-FDA-VETS, http! Device containing the water supply system as described below http: //www.fda.gov/AnimalVeterinary/SafetyHealth customer service, adverse reporting! Breed breeder hens ( 63 weeks old ) stress they undergo the in. Of FBZ at either study site: //www.fda.gov/AnimalVeterinary/SafetyHealth: Safe-Guard AquaSol should always be by., NJ, USA and its affiliates up the measuring device that already an... Of getting one of those cute little coops the instructions in the medication until. Cautions for Safe-Guard AquaSol for chickens Indications, warnings and cautions for Safe-Guard AquaSol was administered orally in water! Ensure that the total amount of deworming stress they undergo a third field effectiveness study was conducted in US... Dose confirmation study was conducted in the US using 550 Cobb breed breeder hens ( 63 weeks old.... May cause gastrointestinal disturbances and hypersensitivity reactions in humans the accuracy of the large intestinal tract management should. Pound given orally for 5 consecutive days a common protocol was implemented in different. The control and 5 mg fenbendazole/kg body weight groups ) was provided non-medicated drinking water used... Accordingly based on regular monitoring 5 consecutive days were necropsied before treatment initiation, and control parasitism... The gross lesions collected during the necropsy of product needed into the measuring device the...

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